Utilizing Roche Cedex Bio analyzer for in process monitoring in biotech production
نویسندگان
چکیده
منابع مشابه
Utilizing Roche Cedex Bio analyzer for in process monitoring in biotech production
Introduction One task during development and control of bioprocesses used for production of recombinant proteins is to deliver fast, accurate and reliable analytical process data. Monitoring of nutrients and metabolites in animal or bacterial cell culture is essential to avoid limitations or toxic accumulation during fermentations that can effect cell growth, viability, product yield and qualit...
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Two Cobas-Bio analyzers were found to have significantly increased imprecision, owing to absorbance errors, when we used rotors pieced together from segments of four to 10 cuvets. The difference in CV between whole/unbroken and four-cuvet or 10-cuvet segment rotors was significant by Student's unpaired t-test (P = 0.038 and less than 0.0001, respectively) and by the Mann-Whitney U test (P less ...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2011
ISSN: 1753-6561
DOI: 10.1186/1753-6561-5-s8-p106